王望，博士/讲师，河南三门峡人。2022年6月获得理学博士学位。2022年7月就职于洛阳师范学院食品与药品学院，担任讲师。近年来陆续在Acta Pharm. Sin. B、Eur. J. Med. Chem.、Bioorg. Med. Chem.等著名国际学术期刊上发表SCI论文11篇，其中第一/共同第一作者7篇。

研究领域和兴趣:

活性天然产物的结构改造和衍生化

蛋白降解靶向嵌合体(PROTACs)的设计与合成

教育经历:

2018.9 – 2022.6   沈阳药科大学   天然药物化学   博士

2015.9 – 2018.7   郑州大学       药物化学       硕士

2011.9 – 2015.7   河南师范大学   化工与制药     学士

工作背景：

2022.7 – 至今   洛阳师范学院   食品与药品学院   讲师

发表代表性论文:

1. Wang W1, Xiong L1, Wu Y, Song Z, Sun D, Li H, Chen L. Synthesis of lathyrane diterpenoid nitrogen-containing heterocyclic derivatives and evaluation of their anti-inflammatory activities. Bioorganic & Medicinal Chemistry. 2022, 56: 116627.

2. Wang W, Li, Y, Li, Y, Sun D, Li H, Chen L. Recent Progress in Oleanolic Acid: Structural Modification and Biological Activity. Current Topics in Medicinal Chemistry. 2021, 22(1): 3-23.

3. Wang W, Yang Y, Liu Y, Sun D, Li H, Chen L. Recent progress in andrographolide derivatization: structural modification and biological activity. Mini-Reviews in Medicinal Chemistry. 2021. 22 (11): 1559-1584

4. Wang W1, Wu Y1, Li C, Yang Y, Li X, Sun D, Li H, Chen L. Synthesis of New Lathyrane Diterpenoid Derivatives from Euphorbia lathyris and Evaluation of Their Anti-Inflammatory Activities. Chemistry & Biodiversity. 2019, 17(2): e1900531.

5. Wang W1, Wu Y, Yang K, Wu C, Tang R, Li H, Chen L. Synthesis of novel andrographolide beckmann rearrangement derivatives and evaluation of their HK2-related anti-inflammatory activities. European Journal of Medicinal Chemistry. 2019, 173: 282-293.

6. Wang W1, Wu Y1, Chen X, Zhang P, Li H, Chen L. Synthesis of new ent-labdane diterpene derivatives from andrographolide and evaluation of their anti-inflammatory activities. European Journal of Medicinal Chemistry. 2019, 162: 70-79.

7. Wu Y1, Yang Y1, Wang W1, Sun D, Liang J, Zhu M, Li H, Chen L. PROTAC technology as a Novel tool to identify the target of lathyrane diterpenoids. Acta Pharmaceutica Sinica B. 2022, 12 (11): 4262-4265